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| UDK 616.741-004.1-089.163 |
ISSN 035-2899, 39(2014) br.3 p.126-131 |
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Original paper Analysis of conjunctival bacterial flora in the preparation of patients for cataract surgery Ispitivanje bakterijske flore vežnjače u pripremi pacijenata za operaciju katarakte
Marija Trenkić Božinović (1), Dragan Veselinović (1, 2),
Branislav Tomašević (1), |
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| Download in pdf format | Summary: In most cases, microorganisms responsible for intraocular infection are identical to the organisms on the ocular surface of the patient’s ocular adnexa. The preoperative and postoperative infection prophylaxis aims to reduce the risk of infection from bacterial flora of the eye and adnexa and to eliminate bacteria that can contaminate the wound during surgery. The aim of our study was the microbiological analysis of the bacterial flora of the conjunctiva, preoperative eradication in terms of prophylaxis of endophthalmitis following cataract surgery and to determine the effectiveness of ofloxacin 0.3 % in bacteria reduction. The study included 120 patients suffering from senile cataract selected at the Department of Ophthalmology, Clinical Centre Niš, divided into two groups of 60 patients. The control group of 60 patients did not receive antibiotics preoperatively. The second group of 60 patients was treated topically with ofloxacin 0.3% in the form of drops, four times a day for four days prior to surgery, and four times for two hours prior to surgery. Examination of the conjunctival flora was carried out using standard microbiological procedures. The conjunctival swabs were collected from all patients at the time of the selection for surgery (the first swab), four days prior to surgery (second swab) and immediately before the operation and on entering the operating room (third swab). In the control group of patients, the first and second conjunctival swabs were positive in 9 and negative in 51 patients. The third swab findings did not change (9 positive and 51 negative swabs). There was no statistically significant difference between the findings of the first, second and third swabs of patients in the control group (χ2 test, p>0.05). In the therapy group of patients, the first and second conjunctival swabs were positive in 6 cases and negative in 54 patients. Detection of the third sample from this group was sterile in all 60 patients. There was a statistically significant difference between the findings of the second and third swabs of patients in the treatment group, ie. there was a correlation between the response to therapy and the outcome of patients (χ2 test, p<0,05). Among the 15 positive conjunctival swab findings the most common cause of infection were Staphylococcus aureus (6 swabs) and Staphylococcus epidermidis (5 swabs), Enterobacter spp. (2 swabs), Proteus mirabilis and Pseudomonas aeruginosa in one swab respectively. Topical ofloxacin 0.3 % for four days prior to surgery, and four times in two hours before the operation is effective in the elimination of the bacterial flora of the conjunctiva and the sterility is achieved in all cases. Key words: bacterial flora, conjunctiva, cataract, prophylaxis, endophthalmitis, ofloxacin 0.3 % Napomena: kompletan tekst rada na srpskom jeziku Note: full text in Serbian |
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Corresponding Address: Marija Trenkić Božinović, Klinika za očne bolesti, Klinički centar Niš, Dr Zorana Đinđića 48, 18000 Niš, Srbija; E-mail: marija.trenkic@gmail.com |
Paper received: 4.6.2014 Paper accepted: 13.6.2014 Paper Internet issues: 26.9.2014 |
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