Journal of Regional Section of Serbian Medical Association in Zajecar

Year 2005     Volumen 30     Number 3
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UDK: 616-002-053.2-074; 577.175.4.088 ISSN 0350-2899, 30(2005) 3 p. 119-122

Advantage of Procalcitonin for Quickly Differentation Bacterial from Viral Infection at Children and Infants

Adnan Bajraktarević (1), Lutvo Sporišević (2), Hakam Khatib (3)
(1) Dom zdravlja, Centar Vrazova - Dispanzer za predškolsku djecu
(2) Hitna pomoć Sarajevo - Pedijatrijski odjel
(3) Odjel za perinatologiju i neonatologiju Ginekološko-akušerske klinike



  Summary: Comparing different studies (American, British, French, Italian, Austrian and Finish) and articles about procalcitonin (PCT) we found out how important it is for a prompt differentiation between bacterial and virus infections in children and infants. It is also a useful indicator of severity of bacterial infections. Future studies will identify the best way for determining and application of PCT concentration, which seems to be very suitable for application in paediatric emergency cases. PCT [1] may be useful in urgent cases for differentiation between bacterial and viral infections in children and for making decisions on antibiotic treatments. We found out that procalcitonin (PCT) is increased in bacterial infections [2], but stays low in viral infections and some other inflammatory diseases. Changes are rapid and the molecule is stable, so it can be potentially a useful marker for distinguishing between bacterial and viral infections. Comparing [3] the PCT with the CRP C reactive protein, interleukin 6 and interferon-alpha we could see that PCT values, higher then others, enable better differentiation between bacterial and viral infections.
Key words: procalcitonin (PCT), CRP, interleukin 6, interferon-alpha, viral infections, bacterial infections.

Note: full text in Serbian
Napomena: kompletan tekst rada na srpskom jeziku

  Corresponding Address:
Adnan Bajraktarević
Husrefa Redžića 13/7, 71000 Sarajevo, Bosna i Hercegovina
mob:0038761-199526; fax: 0038733-555391
  Paper received: 07.07.2005.
Paper accepted: 03.11.2005.
Published online: 16.12.2005.
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