|UDK: 616-002-053.2-074; 577.175.4.088||ISSN 0350-2899, 30(2005) 3 p. 119-122|
Advantage of Procalcitonin for Quickly Differentation Bacterial from Viral Infection at Children and Infants
Adnan Bajraktarević (1), Lutvo Sporišević (2), Hakam Khatib (3)
|Summary: Comparing different studies
(American, British, French, Italian, Austrian and Finish) and articles
about procalcitonin (PCT) we found out how important it is for a prompt
differentiation between bacterial and virus infections in children and
infants. It is also a useful indicator of severity of bacterial
infections. Future studies will identify the best way for determining and
application of PCT concentration, which seems to be very suitable for
application in paediatric emergency cases. PCT  may be useful in urgent
cases for differentiation between bacterial and viral infections in
children and for making decisions on antibiotic treatments. We found out
that procalcitonin (PCT) is increased in bacterial infections , but
stays low in viral infections and some other inflammatory diseases.
Changes are rapid and the molecule is stable, so it can be potentially a
useful marker for distinguishing between bacterial and viral infections.
Comparing  the PCT with the CRP C reactive protein, interleukin 6 and
interferon-alpha we could see that PCT values, higher then others, enable
better differentiation between bacterial and viral infections.
Key words: procalcitonin (PCT), CRP, interleukin 6, interferon-alpha, viral infections, bacterial infections.
Husrefa Redžića 13/7, 71000 Sarajevo, Bosna i Hercegovina
mob:0038761-199526; fax: 0038733-555391
Paper received: 07.07.2005.
Paper accepted: 03.11.2005.
Published online: 16.12.2005.
|Infotrend Crea(c)tive Design||Revised: 20 May 2009|