Journal of Regional Section of Serbian Medical Association in Zajecar

Year 2006     Volumen 31     Number 1-2
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UDK 618.146-006.6-089 ISBN 0350-2899, 31(2006) 1-2 p. 5-7
Original paper

Conization - a method of definite treatment of malignant lesion in early period

Dragoslav Kalinović, Ljubica Milošević, Vera Najdanović-Mandić
Zdravstveni centar Zaječar, Služba za transfuziju krvi



Cervical cancer is the second most frequent cancer in women. It develops slowly and is usually preceded by precancerous conditions which are possible to cure in 100% of cases. In our section, data for five-year period (1998-2002) were retrospectively used, and a number of knife-performed conizations, histopathological verifications after these conizations as well as the ratio of benign, dysplastic changes and zero stadium cancers were monitored. There were only 79 knife-performed conizations and through subsequent histopathological processing 17 benign, 51 dysplastic changes and 11 cancers in situ were detected. Microinvasive cancer of cervix uteri is a microscopical, mostly asymptomatic lesion of cervical epithelium which is diagnosed during routine cytological inspection of cervical mop and colposcopy, and confirmed by focused biopsy. If, during biopsy, there arises any suspicion of microinvasion or signs of invasion exist, conization must be performed in order to reach a definite histopathological diagnosis. In the treatment of these patients the essential thing is to identify cancer with small or no chances at all to turn into a metastasis. Knife-performed conization is a classical excision technique for treatment of pathological cervical lesions with high histopathological grade (H SIL). In our country, as in the world, the number of conizations increases (classical as well as of other techniques), which points to increasingly better prevention diagnosis.
Key words: Conization, malignant lesion, cervics

: kompletan tekst rada na srpskom jeziku
Note: full text in Serbian
  Corresponding Address:
Dragoslav Kalinović
Dunavska 3, 19000 Zaječar
e-mail: kalinovic@ptt.yu
  Paper received: 19.11.2005.
Paper accepted: 16.12.2005.
Published online: 22.09.2006.
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