Journal of Regional Section of Serbian Medical Association in Zajecar

Year 2012     Vol 37     No 3
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      UDK 616.853 ; 616.8-006.6-06

ISSN 035-2899, 37(2012) br.3 p.173-176

Case report

Epilepsy and astrocytoma: correlation, cause and mutual occurrence
Epilepsija i astrocitom: povezanost, uzrok i međusobna pojava

Maja Mladenović
Zdravstveni centar Zaječar, Služba neurologije


INTRODUCTION. Astrocytoma is a brain tumour that originates from astrocytes. The predominant numbers of astrocytomas are the ones with the high degree of malignancy, which account for about 38% of all brain tumours. The overall survival rate in patients with polycystic astrocytomas is about 10 years, in low differentiated astrocytoma it is about 5 years, and with anaplastic astrocytoma about 2 years. (3) The exact number of patients with epilepsy is not known, despite of all the research. It is considered that there are between 4 and 7 people suffering from the disease per 1000 inhabitants in our country. (4) In case of the slow growing astrocytoma it can take from 15 to 25 years after the diagnosis of the disease to the occurrence of epilepsy. (5) CASE REPORT. Patient S.K. (32), was hospitalized in the neurology of the HCC Zaječar because of a series of epileptic attacks of GM type. The disease started at the age of eight with mild headaches, nausea and vomiting. The examination and CT scans revealed expansive changes in the cerebral chamber III. After the surgical procedure at the Neurosurgery, pathological examination confirmed the diagnosis of astrocytoma gr.II. The patient was on an antiepileptic treatment. The patient had to undergo numerous brain surgeries due to recurrent tumour, hematoma, and hydrocephalus. The first epileptic seizure occurred eleven years after the first surgery. Since then, the seizures occur periodically during the winter months, and respond well to the introduction of a new antiepileptic drug. CONCLUSION. In this patient, the period from diagnosis of astrocytoma to the occurrence of epileptic seizure was longer than usual, and it raises the question of the true cause of epilepsy. Why do the seizures occur in almost regular intervals, what can we ascribe them to, and why do they react well to the new medicine? There is hope that we can find the answers to these questions soon.
Key words: astrocytoma, epilepsy, antiepileptic therapy

Napomena: kompletan tekst rada na srpskom jeziku
Note: full text in Serbian
      Corresponding Address:
Maja Mladenovic
Zdravstveni centar Zaječar
Rasadnička bb, 19000 Zaječar
Paper received: 9.04.2012
Paper accepted: 19.5.2012
Paper Internet issues: 27.12.2012

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Timočki medicinski glasnik, Zdravstveni centar Zaječar
Journal of Regional section of Serbian medical association in Zajecar
Rasadnička bb, 19000 Zaječar, Srbija

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