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UDK 616.155.3 |
ISSN 035-2899, 39(2014) br.1 p.20-24 |
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Original paper Iron deficiency anaemia - single center study (Anemija usled deficita gvožđa - naše iskustvo)
Snežana Sretenović, Žaklina Necin-Jovanović, Vesna Stojanović,
Danijela Jovanović |
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Download in pdf format | Summary: Introduction: Anaemia is a term used in clinical practice for decreased haemoglobin concentration, a decrease in number of erythrocytes and a low level of haematocrit. The cause of iron deficiency, isolated or in anaemia, should always be examined, since it can be a consequence of severe diseases. The examination included 110 adult patients with verified anaemia. The aims of this examination were: 1. To determine the average age of the examinees and anaemia distribution in males and females. 2. To determine the distribution of iron and ferritin in serum in patients with anaemia. 3. To determine the organ system the disorder of which is the most common cause of anaemia. 4. To define anaemia distribution according to morphological classification in the examined sample, and transfusional dependence in presentation. Method: Prospective analyses of 110 adult patients with anaemia were made from 15/10/2010 to 15/04/2011, namely over the period of six months. The excluding factor was pregnancy. Certain examinations were conducted in all patients: upper and lower endoscopy, ultrasound of the upper abdomen, male and female urologist examinations, gynaecologist examination and gynaecological ultrasound in female patients. Laboratory analyses were also done: complete blood count, iron and ferritin level test, TIBC, hepatogram, Coomb´s test direct and indirect, as well as the analysis of urine sediment and faecal occult haemorrhage. Statistical data analysis was done by descriptive and analytical methods. The results were presented in tables and charts. Results: The average age of the examinees was 59.71, and female patient prevailed. Iron deficiency anaemia was confirmed in 64.55% examinees, while a low level of ferritin was confirmed in 40.9% of all the examinees. The most common cause of anaemia was located in gastrointestinal tract, verified as ulcus ventriculi, erosio ventriculi, erosio hitus haerniae, ulcus bulbi duodeni , nodduli haemoroidales sanqunans or colitis ulcerosa. 60% of the examinees were transfusion dependent, out of which 41% were with hyposidermic anaemia. Conclusion: Both prevention and the early disease identification are necessary as well as the adequate examination to verify the basic disease which is the cause of anaemia. Iron deficiency anaemia is treated with the substitution of iron preparations in an adequate dose. The treatment should be long enough till the normalization of haemoglobin level, of iron level in serum and of ferritin, while erythrocytes transfusion should be avoided. Key words: anaemia, iron deficiency, diagnosis, treatment, transfusion Napomena: kompletan tekst rada na srpskom jeziku Note: full text in Serbian |
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Corresponding Address: Snežana Sretenović Moravska 8/2; 34000 Kragujevac; Srbija; E-mail: sretenovicsnezana@yahoo.com |
Paper received: 25.12.2013 Paper accepted: 12.2.2014 Paper Internet issues: 20.6.2014 |
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