Journal of Regional Section of Serbian Medical Association in Zajecar

Year 2014     Vol 39     No 4
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      UDK 616.132/.133-07

ISSN 035-2899, 39(2014) br.4 p.171-175

Original paper

Correlation between clinical prediction tests for coronary heart disease and findings on spect myocardial perfusion scintigraphy and coronary angiography
(Korelacija kliničkih testova za predikciju koronarne bolesti i nalaza na spect perfuzionoj scintigrafiji miokarda i koronarnoj angiografiji)

Miloš Stević (1), Marina Vlajković (1), Milena Rajić (1), Goran Koraćević (2), Slobodan Ilić (1)
(1) Centar za nuklearnu medicinu, Klinički centar Niš, (2) Klinika za kardiovaskularne bolesti, Klinički centar Niš


  Download in pdf format   Extended summary: Predictive clinical tests are important diagnostic tools in determining groups of patients who should undergo further diagnostic methods for detection of coronary artery disease. The aim of this study was to determine the correlation between the probability of the existence of the coronary heart disease (CHD) obtained with Duke’s clinical prediction tests for the existence of coronary artery disease and the results obtained by SPECT myocardial perfusion scintigraphy and coronary angiography. Patients and methods: The study included 56 patients with symptoms of angina pectoris (AP), 35 men and 21 women, aging 32-78 years. In all patients, the probability of the existence of coronary artery disease was calculated, i.e. the need for other diagnostic methods, by means of Duke clinical prediction (DCS). The patients subsequently underwent SPECT myocardial perfusion scintigraphy (SPECT MPI) with exercise stress test and with calculating Duke treadmill score (DTS), followed by coronary angiography (CA). The results were statistically analyzed using SPSS statistical tools, non-parametric statistical tests. Results: DCS showed a low CHD probability in 10 (17.9%), while in 46 (82.1%) there was moderate probability. DTS showed low probability in 8 (14.3%) and in 48 (85.7%) high probability of CHD. SPECT MPI resulted in 22 (39.3%) normal and 34 (60.7%) pathologilal states. CA was negative in 21 (37.5%), while in 35 (62.5%) showed significant coronary artery stenosis. In the group with low DCS and DTS probability for CHD there were no perfusion defects in SPECT MPI and no coronary artery stenosis in CA. Conclusion: Predictive clinical tests DCS and DTS, which confirm or reject suspicion of CHD, represent an important diagnostic tool that avoids unnecessary exposure of patients to further diagnostic methods which mean either an invasive diagnostic approach or any unnecessary exposure of patients to ionizing radiation. DCS and DTS have high negative predictive value and are reliable tools for selection of AP patients for further diagnostic modalities.
Keywords: Duke clinical score, Duke treadmill score, perfusion myocardial scintigraphy, Coronary angiography

Napomena: kompletan tekst rada na srpskom jeziku
Note: full text in Serbian
      Corresponding Address:
Miloš Stević
Centar za nuklearnu medicinu, Klinički Centar Niš, Bul. dr Zorana Đinđića 48; 18 000 Niš, Srbija
Rad primljen: 31. 7. 2014. Rad prihvaćen: 1. 8. 2014.
Paper received: 31.7.2014
Paper accepted: 1.8.2014
Paper Internet issues: 17.11.2014
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Timočki medicinski glasnik, Zdravstveni centar Zaječar
Journal of Regional section of Serbian medical association in Zajecar
Rasadnička bb, 19000 Zaječar, Srbija

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