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| UDK 616.132/.133-07 |
ISSN 035-2899, 39(2014) br.4 p.171-175 |
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Original paper Correlation between clinical prediction tests for coronary heart disease and findings on spect myocardial perfusion scintigraphy and coronary angiography (Korelacija kliničkih testova za predikciju koronarne bolesti i nalaza na spect perfuzionoj scintigrafiji miokarda i koronarnoj angiografiji) Miloš Stević (1), Marina Vlajković (1), Milena Rajić (1), Goran Koraćević (2), Slobodan Ilić (1) (1) Centar za nuklearnu medicinu, Klinički centar Niš, (2) Klinika za kardiovaskularne bolesti, Klinički centar Niš |
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| Download in pdf format | Extended summary:
Predictive clinical tests are important diagnostic tools in
determining groups of patients who should undergo further diagnostic
methods for detection of coronary artery disease. The aim of this
study was to determine the correlation between the probability of
the existence of the coronary heart disease (CHD) obtained with
Duke’s clinical prediction tests for the existence of coronary
artery disease and the results obtained by SPECT myocardial
perfusion scintigraphy and coronary angiography. Patients and
methods: The study included 56 patients with symptoms of angina
pectoris (AP), 35 men and 21 women, aging 32-78 years. In all
patients, the probability of the existence of coronary artery
disease was calculated, i.e. the need for other diagnostic methods,
by means of Duke clinical prediction (DCS). The patients
subsequently underwent SPECT myocardial perfusion scintigraphy (SPECT
MPI) with exercise stress test and with calculating Duke treadmill
score (DTS), followed by coronary angiography (CA). The results were
statistically analyzed using SPSS statistical tools, non-parametric
statistical tests. Results: DCS showed a low CHD probability in 10
(17.9%), while in 46 (82.1%) there was moderate probability. DTS
showed low probability in 8 (14.3%) and in 48 (85.7%) high
probability of CHD. SPECT MPI resulted in 22 (39.3%) normal and 34
(60.7%) pathologilal states. CA was negative in 21 (37.5%), while in
35 (62.5%) showed significant coronary artery stenosis. In the group
with low DCS and DTS probability for CHD there were no perfusion
defects in SPECT MPI and no coronary artery stenosis in CA.
Conclusion: Predictive clinical tests DCS and DTS, which confirm or
reject suspicion of CHD, represent an important diagnostic tool that
avoids unnecessary exposure of patients to further diagnostic
methods which mean either an invasive diagnostic approach or any
unnecessary exposure of patients to ionizing radiation. DCS and DTS
have high negative predictive value and are reliable tools for
selection of AP patients for further diagnostic modalities. Keywords: Duke clinical score, Duke treadmill score, perfusion myocardial scintigraphy, Coronary angiography Napomena: kompletan tekst rada na srpskom jeziku Note: full text in Serbian |
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Corresponding Address: Miloš Stević Centar za nuklearnu medicinu, Klinički Centar Niš, Bul. dr Zorana Đinđića 48; 18 000 Niš, Srbija Rad primljen: 31. 7. 2014. Rad prihvaćen: 1. 8. 2014. |
Paper received: 31.7.2014 Paper accepted: 1.8.2014 Paper Internet issues: 17.11.2014 |
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