Journal of Regional Section of Serbian Medical Association in Zajecar

Year 2009     Vol 34     No 2
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      UDK 616.314.2-006-089

ISSN 0350-2899, 34(2009) br 2 p.90-95

Original paper

Mangibular ameloblastoma - Therapeutical options of treatment
Goran Bjelogrlić (1), Vesna Stojanović Kamberović (2), Rade Kosanović(3), Snežana Babac (4), Goran Videnović (5)
(1) Institut za ORL i MFC KC Srbije, Beograd; (2) Dom zdravlja "Zvezdara", Beograd; (3) Klinika za ortorinolaringologiju KBC "Zvezdara", Beograd; (4) Medicinski fakultet Priština; (5) Klinika za MFH, Kosovska Mitrovica


INTRODUCTION: Ameloblastoma is a benign epithelial tumor of odontogenous origin, appearing in mono- or polycystic form, characterised by local aggressive growth, with a tendency of recurrence (in about 30 per cent of cases). It occurs four times more often in the mandible than in the maxilla. The tumor particularly tends to develop in the ramus and the angulus of the mandible. OBJECTIVE OF THE WORK: Analysis of the different applied therapy options in patients with diagnosed and PH verified amelolastoma of the mandible. METHOD: On the basis of the details of the case history, clinical examination (external and intraoral), radiography (orthopan, including computerised tomography and MR if necessary), the chosen method was surgical intervention (enucleation of the tumor-conservative/marginal/segmental-resection of the mandible, hemi-resection of the mandible-radicular, extensive resection of the part of the mandible affected by the tumor extending to the surrounding healthy tissue), including the PH analysis of the tumor. RESULTS: Retrospecive and partially prospectilly study comprised 19 patients with ameloblastoma of the mandible diagnosed by the application of adequate procedures, a very large percentage of them with the tumor in an advanced phase. The average age of the patients was 38.37±12.53 (11-55 years). Eleven patients were males. The clinical picture of the mandible showed a more or less swollen tissue with the teeth dislocated or very shaky; also, there was malocclusion while the prosthesis was becoming increasingly inadequate, more often than not with ulceration on the alveolar ridge. Root resorption, including dislocation, of the teeth in the area affected by the tumor, was noticeable, as well as the presence of a retained tooth. Enucleation was applied on 4 patients, marginal resection on 9 patients, and hemi resection of the mandible on 6 patients. In the period under review recurrence was noticed in 2 patients. There was no malignant alteration. CONCLUSION: The choice of surgical treatment was relevant to the biological nature of the tumor, its histological type, local expansion and possible former recurrence. The chosen therapy was maximally radical resection of the mandible in 78.95 per cent of cases.
Key words: mandibular ameloblastoma, choice of surgical option

Napomena: kompletan tekst rada na srpskom jeziku
Note: full text in Serbian

      Corresponding Address:
Goran Bjeloglić
KC Srbije, Institut za ORL I MFH
Pasterova 2, 11000 Beograd
Paper received: 13.04.2009.
Paper accepted: 24.06.2009.
Published online: 06.08.2009.
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Timočki medicinski glasnik, Zdravstveni centar Zaječar
Journal of Regional section of Serbian medical association in Zajecar
Rasadnička bb, 19000 Zaječar, Srbija

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